What Are Mad Honey Effects?
Feelings of Relaxation with a calm, grounded sensation, gentle buzz and Mild mood lift are some positive effects of mad honey at controlled doses.
Meanwhile side effects of Dizziness, Hallucinations, Delirium and can develop at mild to higher doses. If you were wondering “what does mad honey feel like?” These experiences fairly answer the question.
Mad honey sourced from particular Rhododendron species Rhododendron Ponticum and Rhododendron Luteum in Nepal and Turkey is renowned for delivering unique experiences. This unique experience is the effect caused by the potent biocompound called grayanotoxin found in Mad Honey.
The Science Behind Mad Honey Effects
Grayanotoxin, a potent natural neurotoxin is the active ingredient behind the effects of Mad Honey. Once the Grayanotoxin in Mad Honey reaches Gastrointestinal Tract it is absorbed and passes through intestinal membranes as it is Lipophilic. The grayanotoxin then enters the bloodstream by bypassing the liver and reaches excitable nerves as well as the heart.
Grayanotoxin in blood is absorbed at cellular level and starts affecting the body by blocking sodium ion channels within cell membranes thereby causing prolonged depolarization and cell excitation. This disruption in the transmission of the neurons potentially impacts on excited tissue including the central nervous system and muscle cells.
Historical records of Mad Honey Intoxication
The overdose effects of Mad Honey have been recorded several times in the history books.
- The first one was recorded with Greek Army in Turkey The second was recorded as the defeat of Roman Soldiers
- One case of Mad Honey intoxication in South Korea killed a middle aged man
- Aristotle describes box wood honey with heavy scent, causing healthy individuals to go mad
The Ancient History of Mad Honey Intoxication is evident enough to raise attention for the side effects of Mad Honey that can be fatal with ignorance of dosage limits.
Mad Honey Effects Duration
Wondering, “How long until Mad Honey starts kicking?”
Well, the effects of Mad Honey usually develop between 15-40 minutes after ingestion. Also, there are several factors that affect the time until mad honey starts kicking.
Factors that determine the effects of Mad Honey
- Amount of Mad Honey consumed (larger doses=stronger effects)
- Individual metabolism and level of tolerance
- Potency and availability of Grayanotoxin present in the honey
- Empty stomach where absorption is faster
How long do the effects of Mad Honey Last?
A 2018 study found grayanotoxin’s effects peak within hours and subside in between 24–48 hours (Source: PubMed)
Effects experienced at smaller doses can disappear between 2-3 hours after the consumption while intoxication at higher doses can persist for up to 24 hours and beyond. It is always advised to proceed with caution.
The body eventually eliminates Grayanotoxin unchanged or in partially metabolized form via the urine. Kidneys help in filtering out the Grayanotoxin once the liver processes whatever it can. The effects of Grayanotoxin disappear slowly and the body gradually returns to normal.
Long - Term Effects of Mad Honey
There has not been study or well documented long term effects of Mad Honey. The only possible cases that Mad Honey can effect in long term can be
- Desensitization to small doses
- Psychological dependence (using it repeatedly for the "buzz")
- Potential cause of liver or kidney strain can be expected
The Gurungs who have been using it since a long time have no reported effects over a longer period of time. Instead they seem agile and active even at older ages, with no reported disease
Treatment and Management of Mad Honey Poisoning
Suspected overdose with mad honey should seek immediate medical attention. There is no specific antidote for Grayanotoxin poisoning by mad honey but there are some procedures to alter and minimize the effects.
Activated Charcoal
Ingestion of activated charcoal, if presenting within an hour of ingesting mad honey, can absorb Grayanotoxins.
Intravenous Fluids
Intravenous fluids like atropine and saline infusions are administered to maintain fluid balance, avoid dehydration and maintenance of blood pressure.
Medical attention
Due to the possibility of bradycardia or hypotension, patients should be admitted to a hospital in order to monitor the heart rate and blood pressure.
Respiratory Support
Oxygen therapy or mechanical ventilation for cases in which the patient is experiencing difficulty breathing
Symptoms Monitoring
Continuous monitoring is quite important, as the action of grayanotoxins may extend beyond a few hours.
User Experiences with Mad Honey
Our customers share their stories, showcasing mad honey’s diverse effects:
Let customers speak for us
Frequently Asked Questions
Can Mad Honey Overdose Kill you?
Yes, mad honey can kill you if you neglect the dosage guideline, get intoxicated and fail to seek medical attention when necessary.
Can mad honey poisoning treatment be done at home?
If the effects are simple and minor, taking rest can simply flush the Grayanotoxin simply but if the case is severe you must seek medical help immediately.
Will Mad Honey Soaps and Balms intoxicate me?
Yes, mad honey is toxic to cats and dogs and should be kept far away from them. If accidental ingestion occurs, seek emergency veterinary care immediately.
Will mad honey affect my cats and dogs?
No, products like Mad Honey Soap and Mad Honey Lip Balms don’t affect the Mad Honey itself. You are free to use such products, without fear.